Publications
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma. KM Campbell, M Amouzgar, SM Pfeiffer, TR Howes, E Medina, M Travers, G Steiner, JS Weber, JD Wolchok, J Larkin, FS Hodi, S Boffo, L Salvador, D Tenney, T Tang, MA Thompson, CN Spencer, DK Wells, A Ribas. Cancer Cell (2023) link
Evolution of stickleback spines through independent cis-regulatory changes at HOXDB. JI Wucherpfennig, TR Howes, JN Au, EH Au, GAR Kingman, SD Brady, AL Herbert, TE Reimchen, MA Bell, CB Lowe, AC Dalziel, and DM Kingsley. Nature Ecology & Evolution (2022) link
Impact of checkpoint blockade on cancer vaccine–activated CD8+ T cell responses. PM Santos, J Adamik, TR Howes, S Du, L Vujanovic, S Warren, A Gambotto, JM Kirkwood, and LH Butterfield. Journal of Experimental Medicine (2020) link
Detecting differential copy number variation between groups of samples. CB Lowe, N Sanchez-Luege, TR Howes, SD Brady, RR Daugherty, FC Jones, MA Bell, and DM Kingsley. Genome Research (2018) link
Dorsal spine evolution in threespine sticklebacks via a splicing change in MSX2A. TR Howes, BR Summers, and DM Kingsley. BMC Biology (2017) link
The genomic basis of adaptive evolution in threespine sticklebacks. FC Jones, MG Grabherr, YF Chan, P Russell, E Mauceli, J Johnson, R Swofford, M Pirun, MC Zody, S White, E Birney, S Searle, J Schmutz, J Grimwood, MC Dickson, RM Myers, CT Miller, BR Summers, AK Knecht, SD Brady, H Zhang, AA Pollen, TR Howes, C Amemiya, Broad Institute Genome Assembly Team, ES Lander, F Di Palma, K Lindblad-Toh, DM Kingsley. Nature (2012) link